Encapsulation of Lipid-Soluble Bioactives by Nanoemulsions

Molecules. 2020 Aug 31;25(17):3966. doi: 10.3390/molecules25173966.

Abstract

Lipid-soluble bioactives are important nutrients in foods. However, their addition in food formulations, is often limited by limited solubility and high tendency for oxidation. Lipid-soluble bioactives, such as vitamins A, E, D and K, carotenoids, polyunsaturated fatty acids (PUFA) and essential oils are generally dispersed in water-based solutions by homogenization. Among the different homogenization technologies available, nanoemulsions are one of the most promising. Accordingly, this review aims to summarize the most recent advances in nanoemulsion technology for the encapsulation of lipid-soluble bioactives. Modern approaches for producing nanoemulsion systems will be discussed. In addition, the challenges on the encapsulation of common food ingredients, including the physical and chemical stability of the nanoemulsion systems, will be also critically examined.

Keywords: carotenoids; encapsulation; essential oils; nanoemulsion; vitamin A; vitamin D; vitamin E; vitamin K; β-carotene.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Drug Compounding*
  • Drug Stability
  • Emulsions*
  • Lipids / chemistry*
  • Models, Theoretical
  • Molecular Structure
  • Nanoparticles / chemistry*
  • Nanotechnology* / methods
  • Solubility

Substances

  • Emulsions
  • Lipids