Vapor for lung volume reduction; pros and cons

Expert Rev Respir Med. 2020 Dec;14(12):1189-1195. doi: 10.1080/17476348.2020.1816467. Epub 2020 Sep 24.

Abstract

Introduction: Bronchoscopic lung volume reduction (BLVR) is a novel approach for treatment of emphysema. Several techniques are available to accomplish BLVR including Bronchoscopic Vapor Thermal Ablation (BVTA). This technique is easy to perform and considered safe due to its gradual effect. We discuss BTVA in detail in this editorial.

Areas covered: We discuss our experience with BTVA in detail including patient selection, equipment, procedure, post-procedural care and complications. We also review the literature to determine the pros and cons for its use. Other modalities such as endobronchial valves, coils and lung sealants are also briefly discussed.

Expert opinion: Vapor ablation is a novel and safe approach in inducing lung volume reduction in emphysema patients. The effects are gradual, and therefore potentially making it safer than other minimally invasive modalities. Pneumonitis and infection are common side effects. Just as in other BLVR techniques, a case by case evaluation is needed to determine the right candidate for BTVA. Further larger studies are needed before BTVA becomes standard of care in treatment of patients with emphysema.

Keywords: COPD; Lung volume reduction; bronchoscopy; fluoroscopy; jet-ventilation.

MeSH terms

  • Adult
  • Aged
  • Bronchoscopy / adverse effects
  • Bronchoscopy / methods
  • Female
  • Humans
  • Laser Therapy / adverse effects
  • Laser Therapy / methods
  • Lung / pathology
  • Male
  • Middle Aged
  • Organ Size
  • Patient Selection
  • Pneumonectomy / adverse effects*
  • Pneumonectomy / methods*
  • Pulmonary Emphysema / pathology
  • Pulmonary Emphysema / surgery*
  • Retrospective Studies
  • Treatment Outcome