Achyranthes bidentata polysaccharide can safely prevent NSCLC metastasis via targeting EGFR and EMT

Signal Transduct Target Ther. 2020 Aug 31;5(1):178. doi: 10.1038/s41392-020-00289-2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • A549 Cells
  • Achyranthes / chemistry*
  • Animals
  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Carcinoma, Non-Small-Cell Lung / genetics
  • Carcinoma, Non-Small-Cell Lung / pathology
  • ErbB Receptors / genetics
  • Gene Expression Regulation, Neoplastic / drug effects
  • Humans
  • Mice
  • Neoplasm Metastasis
  • Polysaccharides / chemistry
  • Polysaccharides / pharmacology*
  • Xenograft Model Antitumor Assays

Substances

  • Polysaccharides
  • EGFR protein, human
  • ErbB Receptors