Severe systemic delayed dermatitis in a patient with nickel-titanium sterilization microinserts perforating the uterus

Contraception. 2020 Dec;102(6):430-432. doi: 10.1016/j.contraception.2020.08.007. Epub 2020 Aug 29.

Abstract

We report a case of severe systemic delayed dermatitis in a patient with nickel-titanium sterilization microinserts placement complicated by uterine perforation and polyethylene terephthalate (PET) exposure. We hypothesize that delayed dermatitis may be caused by the exposure of PET fibers in this patient with underlying autoimmune disorder. Further research on the use of PET and the potential of systemic dermatologic reactions when exposure occurs is needed, especially when considering the inclusion of PET in future implant device development.

Keywords: Dermatitis; Microinserts; Nickel allergy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dermatitis, Contact / diagnosis*
  • Device Removal
  • Female
  • Humans
  • Nickel / administration & dosage
  • Nickel / adverse effects*
  • Polyethylene Terephthalates / adverse effects*
  • Sterilization
  • Sterilization, Tubal / adverse effects*
  • Sterilization, Tubal / instrumentation
  • Sterilization, Tubal / methods
  • Titanium / administration & dosage
  • Titanium / adverse effects*
  • Treatment Outcome
  • Uterine Perforation*
  • Uterus / surgery*

Substances

  • Polyethylene Terephthalates
  • Nickel
  • Titanium