Luminescent Bimetallic IrIII /AuI Peptide Bioconjugates as Potential Theranostic Agents

Andrés Luengo; Isabel Marzo; Matthew Reback; Isabelle M Daubit; Vanesa Fernández-Moreira; Nils Metzler-Nolte; M Concepción Gimeno

doi:10.1002/chem.202003633

Luminescent Bimetallic Ir^III /Au^I Peptide Bioconjugates as Potential Theranostic Agents

Chemistry. 2020 Sep 21;26(53):12085. doi: 10.1002/chem.202003633. Epub 2020 Aug 31.

Authors

Andrés Luengo¹, Isabel Marzo², Matthew Reback³, Isabelle M Daubit³, Vanesa Fernández-Moreira¹, Nils Metzler-Nolte³, M Concepción Gimeno¹

Affiliations

¹ Departamento de Química Inorgánica, Instituto de Síntesis QuímicayCatálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza, 50009, Zaragoza, Spain.
² Departamento de Bioquímica y Biología Celular, Universidad de Zaragoza-CSIC, 50009, Zaragoza, Spain.
³ Inorganic Chemistry I-Bioinorganic Chemistry, Faculty of Chemistry and Biochemistry, Ruhr-Universität Bochum, Universitätsstrasse 150, 44801, Bochum, Germany.

PMID: 32865841
DOI: 10.1002/chem.202003633

Abstract

Invited for the cover of this issue are Vanesa Fernández-Moreira, Nils Metzler-Nolte, M. Concepción Gimeno and co-workers at Universidad de Zaragoza and Ruhr-Universität Bochum. The image depicts the reported bimetallic bioconjugates as planes directing the gold fragment towards the target (lysosomes). Read the full text of the article at 10.1002/chem.202002067.

MeSH terms

Gold / chemistry
Humans
Peptides*
Precision Medicine*

Substances

Peptides
Gold