Efficacy of silver diamine fluoride and sodium fluoride in inhibiting enamel erosion: an ex vivo study with primary teeth

Eur Arch Paediatr Dent. 2021 Jun;22(3):387-392. doi: 10.1007/s40368-020-00559-1. Epub 2020 Aug 28.

Abstract

Purpose: To assess the efficacy of silver diamine fluoride (SDF) and sodium fluoride (NaF) in inhibiting enamel erosion in primary teeth.

Methods: 80 primary canine teeth were immersed for 24 h in 2% NaF, 10% SDF, or distilled water. Afterward, some of them underwent a 10-min acid challenge using either 1% or 10% citric acid while others did not. Specimens selected for negative controls were immersed in distilled water but not exposed to the acids, whereas those selected for positive controls were not only immersed in distilled water, but also exposed to the acids. Following, 3-mL samples were collected for calcium and phosphorus analysis by an atomic emission spectrometer.

Results: 1% acid caused higher phosphorus loss in the positive control group than in the others (no differences between them). Regarding 10% acid, the SDF group showed lower phosphorus loss compared to the positive control and NaF groups. From calcium loss analysis, SDF and NaF groups presented no significant difference when compared to the positive control groups after both acidic challenges.

Conclusion: Considering phosphorus loss values, 10% SDF seems to be effective in inhibiting enamel erosion after 1% and 10% citric acid challenges, whereas 2% NaF only after 1% citric acid challenge. Regarding calcium loss values, both fluoride agents seem to have no impact on inhibiting enamel erosion after 1% and 10% citric acid challenges.

Keywords: Deciduous tooth; Silver diamine fluoride; Sodium fluorides; Tooth demineralization; Tooth erosion.

MeSH terms

  • Dental Enamel
  • Fluorides
  • Fluorides, Topical
  • Humans
  • Quaternary Ammonium Compounds
  • Silver Compounds
  • Sodium Fluoride*
  • Tooth Erosion* / chemically induced
  • Tooth Erosion* / prevention & control
  • Tooth, Deciduous

Substances

  • Fluorides, Topical
  • Quaternary Ammonium Compounds
  • Silver Compounds
  • Sodium Fluoride
  • silver diamine fluoride
  • Fluorides