Opportunities for the federal government to advance necrotizing enterocolitis research

Pediatr Res. 2020 Aug;88(Suppl 1):56-59. doi: 10.1038/s41390-020-1081-5.

Abstract

Background: Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in the neonatal ICU with minimal progress in the research.

Methods: Federal webpages were queried to look for funding opportunity announcements (FOAs) and to develop lists of funded projects on NEC to identify gaps in NEC-related research topics.

Results: Over the past 30 years, the National Institutes of Health (NIH) issued two FOAs to stimulate research on NEC with $4.1 million set aside for the first year of respective funding. We identified 23 recently funded studies of which 18 were research projects, 4 training grants, and 1 conference grant support. Only one grant focused on parent and family engagement in the NICU.

Conclusion: There are significant research gaps that can be addressed with adequate funding from the federal government on the prevention and treatment of NEC.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Clinical Trials as Topic
  • Enterocolitis, Necrotizing / prevention & control*
  • Enterocolitis, Necrotizing / therapy*
  • Family Health
  • Federal Government
  • Financing, Government*
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Newborn, Diseases
  • Intensive Care Units, Neonatal
  • Intensive Care, Neonatal / organization & administration*
  • National Institutes of Health (U.S.)
  • Neonatology / organization & administration*
  • Research Design
  • Research Support as Topic
  • Treatment Outcome
  • United States