Single cell transcriptomics comes of age

Sarah Aldridge; Sarah A Teichmann

doi:10.1038/s41467-020-18158-5

Single cell transcriptomics comes of age

Nat Commun. 2020 Aug 27;11(1):4307. doi: 10.1038/s41467-020-18158-5.

Authors

Sarah Aldridge¹, Sarah A Teichmann^{2

3}

Affiliations

¹ Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB1 1SA, UK.
² Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB1 1SA, UK. st9@sanger.ac.uk.
³ Theory of Condensed Matter Group, Cavendish Laboratory/Department of Physics, University of Cambridge, JJ Thomson Ave, Cambridge, CB3 OHE, UK. st9@sanger.ac.uk.

Abstract

Single cell transcriptomics technologies have vast potential in advancing our understanding of biology and disease. Here, Sarah Aldridge and Sarah Teichmann review the last decade of technological advancements in single-cell transcriptomics and highlight some of the recent discoveries enabled by this technology.

Publication types

Historical Article
Review

MeSH terms

Animals
Computational Biology / history
Computational Biology / methods
Computational Biology / trends*
Forecasting
Gene Expression Profiling / history
Gene Expression Profiling / methods
Gene Expression Profiling / trends*
History, 21st Century
Humans
Single-Cell Analysis / history
Single-Cell Analysis / methods
Single-Cell Analysis / trends*
Transcriptome / physiology*