3D printing promotes the development of drugs

Biomed Pharmacother. 2020 Nov:131:110644. doi: 10.1016/j.biopha.2020.110644. Epub 2020 Aug 24.

Abstract

3D printing is an emerging field that can be found in medicine, electronics, aviation and other fields. 3D printing, with its personalized and highly customized characteristics, has great potential in the pharmaceutical industry. We were interested in how 3D printing can be used in drug fields. To find out 3D printing's application in drug fields, we collected the literature by combining the keywords "3D printing"/"additive manufacturing" and "drug"/"tablet". We found that 3D printing technology has the following applications in medicine: firstly, it can print pills on demand according to the individual condition of the patient, making the dosage more suitable for each patient's own physical condition; secondly, it can print tablets with specific shape and structure to control the release rate; thirdly, it can precisely control the distribution of cells, extracellular matrix and biomaterials to build organs or organ-on-a-chip for drug testing; finally, it could print loose porous pills to reduce swallowing difficulties, or be used to make transdermal microneedle patches to reduce pain of patients.

Keywords: 3D printing; drug delivery; drug development; precise pharmaceutical technology; review.

Publication types

  • Review

MeSH terms

  • Drug Delivery Systems / methods
  • Drug Delivery Systems / trends*
  • Drug Development / methods
  • Drug Development / trends*
  • Humans
  • Precision Medicine / methods
  • Precision Medicine / trends*
  • Printing, Three-Dimensional / trends*
  • Tablets
  • Technology, Pharmaceutical / methods
  • Technology, Pharmaceutical / trends*

Substances

  • Tablets