Lung transplantation is a crucial component in the treatment of end-stage lung disease in infants. Traditionally, most lung transplants have been performed in older children and adults, resulting in a scarcity of data for infant patients. To address the challenges unique to this age group, novel strategies to provide the best preoperative, intraoperative, and postoperative care for these youngest patients are paramount. We review recent advances in bridge-to-transplantation therapy, including the use of a paracorporeal lung assist device, and differences in surgical technique, including bronchial artery revascularization, for incorporation into the overarching treatment strategy for infants undergoing lung transplantation.
Keywords: artificial organs/ support devices: lung; clinical research/ practice; lung disease: congenital; lung transplantation/ pulmonology; pediatrics; surgical technique.
© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons.