Author response to "lack of benefit from low dose computed tomography in screening for lung cancer"

Kai-Lin Huang; Shih-Yuan Wang; Wan-Chen Lu; Ya-Hui Chang; Jian Su; Yen-Ta Lu

doi:10.1186/s12890-020-01247-y

Author response to "lack of benefit from low dose computed tomography in screening for lung cancer"

BMC Pulm Med. 2020 Aug 26;20(1):226. doi: 10.1186/s12890-020-01247-y.

Authors

Kai-Lin Huang^{1

2}, Shih-Yuan Wang¹, Wan-Chen Lu¹, Ya-Hui Chang¹, Jian Su^{3

4}, Yen-Ta Lu^{5

6}

Affiliations

¹ Department of Pharmacy, MacKay Memorial Hospital, No. 92, Sec. 2, Zhongshan N. Rd, Taipei City, 10449, Taiwan.
² Mackay Junior College of Medicine, Nursing, and Management, No.92, Shengjing Road, Beitou District, Taipei, 11272, Taiwan.
³ Department of Chest Medicine, MacKay Memorial Hospital, No. 92, Sec. 2, Zhongshan N. Rd, Taipei City, 10449, Taiwan. jiansu@mmh.org.tw.
⁴ Department of Medicine, Mackay Medical College, No.46, Sec. 3, Zhongzheng Rd., Sanzhi Dist, New Taipei City, 252, Taiwan. jiansu@mmh.org.tw.
⁵ Department of Chest Medicine, MacKay Memorial Hospital, No. 92, Sec. 2, Zhongshan N. Rd, Taipei City, 10449, Taiwan. ytlhl@mmh.org.tw.
⁶ Department of Medicine, Mackay Medical College, No.46, Sec. 3, Zhongzheng Rd., Sanzhi Dist, New Taipei City, 252, Taiwan. ytlhl@mmh.org.tw.

Abstract

We explain to Dr. Benjamin (corresponding author) about why low-dose computed tomography reduce lung cancer mortality without significantly reducing all-cause mortality. We also conduct an up-to-date meta-analysis to evaluate low-dose computed tomography clinical effectiveness compared with usual care of lung cancer screening.

Keywords: LDCT; Low-dose computed tomography; Lung cancer screening; Meta-analysis; Mortality.

Publication types

Letter
Comment

MeSH terms

Early Detection of Cancer*
Humans
Lung Neoplasms*
Mass Screening
Tomography, X-Ray Computed
Treatment Outcome