Efficacy and safety evaluation of acupoint embedding for patients with ulcerative colitis: A protocol of systematic review and meta-analysis

Medicine (Baltimore). 2020 Aug 21;99(34):e21812. doi: 10.1097/MD.0000000000021812.

Abstract

Background: Ulcerative colitis is a recurring digestive disease characterized by inflammation in the intestinal tract, which seriously affects the life of the patient. In recent years, it has played a role in obesity, osteoporosis, and gastrointestinal disorders, and has received more and more attention. However, there are no clear conclusions about its effectiveness and safety in the treatment of UC.

Method and analysis: This systematic review will collect 7 databases, including Web of science, Pubmed, Embase, VIP, Wanfang, CNKI, and the Chinese Biomedical Literature Database (CBM), to collect all eligible RCTs from database inception to December 31, 2019. The 2 researchers will rigorously follow the selection process, including study screening, data extraction, and quality assessment. The primary outcome is clinical effectiveness. The main software used in this study is Review Manager V5.3 software.

Result: This study will provide a meaningful and comprehensive evaluation on the effectiveness and safety of acupoints embedding for UC.

Conclusion: This meta-analysis was designed to provide clinicians with valid evidence regarding acupoint embedding for UC.

Inplasy registration number: INPLASY202040166.

MeSH terms

  • Acupuncture Therapy / adverse effects
  • Acupuncture Therapy / methods*
  • Catgut*
  • Colitis, Ulcerative / blood
  • Colitis, Ulcerative / therapy*
  • Cytokines / blood
  • Humans
  • Meta-Analysis as Topic
  • Prostheses and Implants
  • Randomized Controlled Trials as Topic
  • Research Design
  • Severity of Illness Index
  • Systematic Reviews as Topic

Substances

  • Cytokines