Identification of long non-coding RNAs in insects genomes

Fabrice Legeai; Thomas Derrien

doi:10.1016/j.cois.2015.01.003

Identification of long non-coding RNAs in insects genomes

Curr Opin Insect Sci. 2015 Feb:7:37-44. doi: 10.1016/j.cois.2015.01.003. Epub 2015 Jan 13.

Authors

Fabrice Legeai¹, Thomas Derrien²

Affiliations

¹ INRA, UMR1349, Institute of Genetics, Environment and Plant Protection, Domaine de la Motte, BP35327, 35653 Le Rheu cedex, France; IRISA/INRIA GenScale, Campus Beaulieu, 35000 Rennes, France. Electronic address: fabrice.legeai@rennes.inra.fr.
² CNRS, UMR 6290, Institut de Génétique et Développement de Rennes, Université de Rennes 1, 2 Avenue du Pr. Léon Bernard, 35000 Rennes, France.

PMID: 32846672
DOI: 10.1016/j.cois.2015.01.003

Abstract

The development of high throughput sequencing technologies (HTS) has allowed researchers to better assess the complexity and diversity of the transcriptome. Among the many classes of non-coding RNAs (ncRNAs) identified the last decade, long non-coding RNAs (lncRNAs) represent a diverse and numerous repertoire of important ncRNAs, reinforcing the view that they are of central importance to the cell machinery in all branches of life. Although lncRNAs have been involved in essential biological processes such as imprinting, gene regulation or dosage compensation especially in mammals, the repertoire of lncRNAs is poorly characterized for many non-model organisms. In this review, we first focus on what is known about experimentally validated lncRNAs in insects and then review bioinformatic methods to annotate lncRNAs in the genomes of hexapods.

Publication types

Review