Objective: To explore how people experience organ donation decision-making under the conditions of an opt-in, opt-out or no-objection registration system.
Design: A between-subjects experimental 3 × 2 design (registration system x preselection). Participants (N = 1312) were presented with a description of one of the three registration systems and went through a mock donor registration process. In half of the conditions, the default option of the system was visualized by a ticked box. After, participants answered questions about their perceived autonomy and perceived effective decision-making.
Main outcome measurements: Perceived autonomy, perceived decision effectiveness and registration choice.
Results: The preselected box did not impact any of the outcomes. Participants had higher perceived autonomy under the conditions of an opt-in system. There were no differences in effective decision-making across conditions. Registration choices did differ across conditions and educational levels. In the opt-in system, participants more often made an active decision. Lower-educated participants were more likely to choose to do nothing, while higher-educated people more often made an active decision, especially in the no-objection system.
Conclusion: Where the opt-out system potentially leads to the highest number of donors, the opt-in system seems better in terms of preserving people's autonomy and motivating people to make an active decision.
Keywords: Defaults; autonomy; effective decision-making; no-objection system; registration choices.