Impact of a comprehensive functional rehabilitation programme on the quality of life of the oncological patient with dyspnoea

Med Clin (Barc). 2021 Jul 9;157(1):10-16. doi: 10.1016/j.medcli.2020.05.058. Epub 2020 Aug 22.
[Article in English, Spanish]

Abstract

Background: Dyspnoea is one of leading causes of loss of autonomy in patients with advanced-stage cancer. Pharmacological measures achieve a reduction of the symptom, but without generalizing this improvement to functionality. We propose the inclusion of a comprehensive functional rehabilitation programme. The purpose is to test the efficacy of an integral respiratory rehabilitation programme to improve autonomy levels and relieve cancer-related dyspnoea.

Methods: Experimental design, prospective, longitudinal, randomized study based on a parallel fixed allocation scheme using an experimental group and a control group. The intervention group participated in comprehensive functional rehabilitation, while the control group only received standard drug treatment. Single blind masking, but statistical analysis was performed by non-study personnel.

Results: Final sample of 113 individuals, 52 in the control group and 61 in the experimental group, from the Oncology Unit of the University Hospital Complex of Salamanca. Statistically significant differences (are observed) between the members of both groups in the levels of functionality (p = .000), in the levels of dyspnoea (p =.001) and in the sub-items of the Euro-QOL questionnaire, except in the sub-item related to pain (p = .311). No major adverse effects or side effects are observed.

Conclusion: Non-pharmacological interventions using a comprehensive functional rehabilitation programme improve functionality and relieve dyspnoea in cancer patients.

Keywords: Cancer; Cáncer; Disnea; Dyspnoea; Funcionalidad; Functionality; Rehabilitación; Rehabilitation.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Dyspnea* / etiology
  • Humans
  • Physical Therapy Modalities
  • Prospective Studies
  • Quality of Life*
  • Single-Blind Method