A total of 189 new cases of gastric cancer in Sheyang County from 2014 to 2018 were selected as the case group, and 189 other people without gastric cancer were matched according to age and gender as the control group. A case-control study was conducted on the relationship between drinking water and gastric cancer. After adjusting BMI, family annual income, dietary taste, monthly pickle consumption, monthly chili consumption, monthly soy product consumption, whether experiencing misfortune, whether suffering from superficial gastritis, whether having family history of gastric cancer, the results of multivariate logistic regression showed that compared with those who had no sources of pollution at the end of drinking water 10 years ago and who mainly consumed boiled water, those who had sources of pollution at the end of drinking water 10 years ago and who only drank raw water had a higher risk of stomach cancer ［OR (95%CI) were 2.20 (1.13-4.29), 6.12 (1.25-29.93)］; Compared with drinking water source from tap water, the risk of stomach cancer of those who drink clean water is lower ［OR (95%CI): 0.55 (0.35-0.85)］; And those who drink more water every day have a lower risk of stomach cancer ［OR (95%CI): 0.67 (0.48-0.92)］.
选择2014—2018年射阳县189例胃癌新发病例作为病例组，按照年龄、性别匹配189名其他未患胃癌人群作为对照组，开展居民饮水情况与胃癌关联的病例对照研究。多因素logistic回归模型结果显示，调整体重指数、家庭年收入、饮食口味、每月腌菜食用量、每月辣椒食用量、每月豆制品食用量、经历不幸、患浅表性胃炎、胃癌家族史因素后，与10年前饮水末梢无污染源、饮用开水为主者相比，10年前饮水末梢有污染源、只喝生水者胃癌的患病风险较高［OR（95%CI）值分别为2.20（1.13~4.29）、6.12（1.25~29.93）］；与饮水来源为自来水相比，饮用净水处理后水者胃癌患病风险较低［OR（95%CI）：0.55（0.35~0.85）］；每天饮水量较多者胃癌患病风险较低［OR（95%CI）：0.67（0.48~0.92）］。.
Keywords: Case-control study; Drinking water; Gastric cancer.