[Retrospective analysis of primary parapharyngeal space tumors]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Aug;34(8):743-747. doi: 10.13201/j.issn.2096-7993.2020.08.015.
[Article in Chinese]

Abstract

Objective:To explore the clinical feature and surgical treatment of patients with parapharyngeal space tumors. Method:A retrospective review of 214 cases with parapharygeal space tumors treated. The data on clinical manifestations, imaging examinations, pathological types, surgical approach, and postoperative complications were reviewed. Result:Of the 214 cases, the tumor was benign in nature in 135 cases(63.1%) and malignant in 79 cases(36.9%). There was no gender difference in the incidence of benign tumors, and the ratio of male to female was 1:1. The incidence of malignant tumors was higher in males than in females, and the ratio was 3.3:1. Regardless of benign and malignant tumors, the high incidence age is 40-59. Two-thirds of cases of parapharyngeal space tumors had different degrees of peripheral structural invasion. The most common cases involving the skull base were 76 cases(35.5%), followed by blood vessels and nerves, 24 cases(11.2%) and 16 cases(7.5%),respectively. Complications occurred in 65 patients(31.4%), the most common complications were hoarseness caused by X-cranial nerve palsy. Conclusion:There are various pathological types of parapharyngeal space tumors, and surgery is the first choice for parapharyngeal space tumors. The surgical plan should be made according to the imaging examinations, lesions, and the pathology et al. The risk of complications should be fully informed before the operation, and the cooperation of the patients should be obtained.

目的:探讨原发性咽旁间隙肿瘤的临床特点及外科治疗方法。 方法:回顾性分析214例原发性咽旁间隙肿瘤患者的临床资料,对其临床表现、影像学评估、病理类型、手术径路选择及并发症发生等进行分析。 结果:214例咽旁间隙肿瘤患者中,良性135例(63.1%),恶性79例(36.9%);良性肿瘤发病无性别差异,男∶女为1∶1,恶性肿瘤发病率男性高于女性,男∶女为3.3∶1,无论良恶性肿瘤,其高发年龄段为40~59岁。咽旁间隙肿瘤中2/3的患者有不同程度的周围结构侵犯,累及颅底者最为常见,为76例(35.5%),其次为血管和神经,分别为24例(11.2%)和16例(7.5%)。65例(31.4%)术后发生并发症,常见并发症为第X脑神经麻痹引起的声嘶。 结论:咽旁间隙肿瘤病理类型多样,手术是治疗咽旁间隙肿瘤的主要手段,应根据影像学检查、病变部位、性质等综合考虑,选择合适的手术方案,术前应充分告知并发症的风险,取得患者的配合。.

Keywords: clinical feature; parapharyngeal space tumors; surgical procedures,operative.

MeSH terms

  • Female
  • Humans
  • Male
  • Parapharyngeal Space
  • Pharyngeal Neoplasms*
  • Postoperative Complications
  • Retrospective Studies
  • Skull Base

Grants and funding

国家863计划(No: 2015AA8092017D); 解放军总医院医疗大数据研发项目(No: 2017MBD-018)