Insights into self-healing behavior and mechanism of dicalcium phosphate dihydrate coating on biomedical Mg

Qiangsheng Dong; Xingxing Zhou; Yuanjia Feng; Kun Qian; Huan Liu; Mengmeng Lu; Chenglin Chu; Feng Xue; Jing Bai

doi:10.1016/j.bioactmat.2020.07.019

Insights into self-healing behavior and mechanism of dicalcium phosphate dihydrate coating on biomedical Mg

Bioact Mater. 2020 Aug 12;6(1):158-168. doi: 10.1016/j.bioactmat.2020.07.019. eCollection 2021 Jan.

Authors

Qiangsheng Dong^{1

2}, Xingxing Zhou¹, Yuanjia Feng¹, Kun Qian^{1

2}, Huan Liu³, Mengmeng Lu⁴, Chenglin Chu^{1

2}, Feng Xue^{1

2}, Jing Bai^{1

2}

Affiliations

¹ School of Materials Science and Engineering, Jiangsu Key Laboratory for Advanced Metallic Materials, Southeast University, Nanjing, 211189, China.
² Institute of Medical Devices (Suzhou), Southeast University, Suzhou, 215000, China.
³ College of Mechanics and Materials, Hohai University, Nanjing, 211100, China.
⁴ Department of Oral Implantology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, 210029, China.

Abstract

Self-healing coatings have been developed as smart surface coatings for Mg and its alloys to retain local corrosion from the coating damages. In this study, we prepared dicalcium phosphate dihydrate (DCPD) coating on biomedical Mg, and found that the artificial scratches in DCPD coating can be efficiently sealed by anti-corrosive products in both Hank's and normal saline (NS) solutions. Besides, the in-depth study revealed that DCPD was served as not only a physical barrier but also a self-healing agent, demonstrating an autonomous self-healing coating without embedded extra corrosion inhibitors. Moreover, Hank's solution provided foreign-aid film-forming ions to promote self-healing behavior. The findings might offer new opportunities for further studies and applications of efficient self-healing coatings on biodegradable Mg implants.

Keywords: Coating; Corrosion; Magnesium; Microstructure; Self-healing.