Abstract
Coinfection of SARS-CoV-2/Mycobacterium tuberculosis (MTB) in patients with HIV/AIDS has not been previously reported. Here, we present two cases of coinfection of SARS-CoV-2 and MTB in patients with HIV. The first case is a 39-year-old patient who was admitted with a 7-day history of fever, myalgia, headache, and cough. The second patient is a 43-year-old man who had a 1-month history of cough with hemoptoic sputum, evolving to mild respiratory distress in the last 7 days. Both patients already had pulmonary tuberculosis and subsequently developed SARS-CoV-2 infection during the 2020 pandemic. Nonadherence to antiretroviral treatment may have been a factor in the clinical worsening of the patients.
MeSH terms
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Adult
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Anti-HIV Agents / therapeutic use
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Betacoronavirus / pathogenicity
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COVID-19
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Coinfection
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Coronavirus Infections / drug therapy
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Coronavirus Infections / immunology
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Coronavirus Infections / microbiology*
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Coronavirus Infections / virology
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Cough / drug therapy
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Cough / immunology
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Cough / microbiology*
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Cough / virology
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HIV / pathogenicity
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HIV Infections / drug therapy
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HIV Infections / immunology
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HIV Infections / microbiology*
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HIV Infections / virology
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Humans
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Male
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Mycobacterium tuberculosis / pathogenicity
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Pandemics
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Patient Compliance / psychology*
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Pneumonia, Viral / drug therapy
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Pneumonia, Viral / immunology
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Pneumonia, Viral / microbiology*
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Pneumonia, Viral / virology
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Respiratory Distress Syndrome / drug therapy
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Respiratory Distress Syndrome / immunology
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Respiratory Distress Syndrome / microbiology*
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Respiratory Distress Syndrome / virology
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SARS-CoV-2
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Tomography, X-Ray Computed
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Tuberculosis, Pulmonary / drug therapy
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Tuberculosis, Pulmonary / immunology
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Tuberculosis, Pulmonary / microbiology*
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Tuberculosis, Pulmonary / virology