Therapeutic potential of tricarboxylic acid cycle metabolite itaconate in cardiovascular diseases

EBioMedicine. 2020 Sep:59:102938. doi: 10.1016/j.ebiom.2020.102938. Epub 2020 Aug 15.
No abstract available

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use
  • Cardiovascular Diseases / drug therapy
  • Cardiovascular Diseases / metabolism*
  • Citric Acid Cycle
  • Gene Expression Regulation / drug effects
  • Gene Regulatory Networks* / drug effects
  • Humans
  • Succinates / metabolism*
  • Succinates / pharmacology
  • Succinates / therapeutic use

Substances

  • 4-octyl itaconate
  • Anti-Inflammatory Agents
  • Succinates
  • dimethyl itaconate
  • itaconic acid