Identification of Transcription Factors Regulating SARS-CoV-2 Entry Genes in the Intestine

Cell Mol Gastroenterol Hepatol. 2021;11(1):181-184. doi: 10.1016/j.jcmgh.2020.08.005. Epub 2020 Aug 15.

Authors

L Chen¹, A Marishta², C E Ellison², M P Verzi³

Affiliations

¹ Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, New Jersey; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey. Electronic address: lchen@dls.rutgers.edu.
² Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, New Jersey.
³ Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, New Jersey; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey; Rutgers Center for Lipid Research, New Brunswick, New Jersey. Electronic address: verzi@biology.rutgers.edu.

No abstract available

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Angiotensin-Converting Enzyme 2 / metabolism
Animals
CDX2 Transcription Factor / genetics
CDX2 Transcription Factor / metabolism
COVID-19 / genetics
COVID-19 / metabolism
COVID-19 / virology*
Disease Models, Animal
Erythroid-Specific DNA-Binding Factors / genetics
Hepatocyte Nuclear Factor 4 / genetics
Humans
Intestinal Mucosa / metabolism
Intestinal Mucosa / virology
Intestines / virology
Mice
Receptors, Virus / genetics*
SARS-CoV-2 / genetics*
SARS-CoV-2 / metabolism
Serine Endopeptidases / metabolism
Smad4 Protein / genetics
Spike Glycoprotein, Coronavirus / genetics
Transcription Factors / genetics*
Transcription Factors / metabolism
Virus Internalization

Substances

CDX2 Transcription Factor
Erythroid-Specific DNA-Binding Factors
Hepatocyte Nuclear Factor 4
Receptors, Virus
Smad4 Protein
Spike Glycoprotein, Coronavirus
Transcription Factors
Ace2 protein, mouse
Angiotensin-Converting Enzyme 2
Serine Endopeptidases
TMPRSS2 protein, mouse

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