Luspatercept

Excerpt

Luspatercept is a medication used to manage and treat anemia in myelodysplastic syndromes, primary myelofibrosis, and beta-thalassemia. It is a recombinant fusion protein that binds transforming growth factor-beta ligands to reduce SMAD2 and SMAD3 signaling. This activity describes the indications, actions, and contraindications for luspatercept as a valuable agent in the management when applicable for interprofessional team members.