Clinical and pathological features of Kaposi sarcoma herpesvirus-associated inflammatory cytokine syndrome

AIDS. 2020 Nov 15;34(14):2097-2101. doi: 10.1097/QAD.0000000000002669.

Abstract

: Kaposi sarcoma Herpesvirus (KSHV)-associated inflammatory cytokine syndrome (KICS) is an uncommon but aggressive human Kaposi sarcoma herpesvirus associated disorder that is mostly reported in people living with HIV. The diagnosis of KICS is based on clinical criteria, and, in contrast to other KSHV-related malignancies, characteristic pathological features have not yet been described. We report novel clinical and pathological features in an HIV-1 infected patient diagnosed with KICS.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents, Phytogenic / therapeutic use*
  • Antiretroviral Therapy, Highly Active
  • Cytokines / adverse effects*
  • Cytokines / blood
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • Herpesvirus 8, Human / immunology
  • Herpesvirus 8, Human / isolation & purification*
  • Homosexuality, Male
  • Humans
  • Inflammation / complications
  • Inflammation / drug therapy*
  • Inflammation / virology
  • Interleukin-10
  • Interleukin-6
  • Male
  • Sarcoma, Kaposi / complications
  • Sarcoma, Kaposi / drug therapy*
  • Sarcoma, Kaposi / pathology
  • Sarcoma, Kaposi / virology*
  • Treatment Outcome

Substances

  • Antineoplastic Agents, Phytogenic
  • Cytokines
  • IL10 protein, human
  • IL6 protein, human
  • Interleukin-6
  • Interleukin-10