A near-infrared fluorescent probe for hydrogen polysulfides detection with a large Stokes shift

Fan Zhang; Jinliang Han; Jingpei Wang; Xi Li; Yangang Wang; Benhua Wang; Xiangzhi Song

doi:10.1016/j.saa.2020.118755

A near-infrared fluorescent probe for hydrogen polysulfides detection with a large Stokes shift

Spectrochim Acta A Mol Biomol Spectrosc. 2020 Dec 5:242:118755. doi: 10.1016/j.saa.2020.118755. Epub 2020 Aug 1.

Authors

Fan Zhang¹, Jinliang Han¹, Jingpei Wang¹, Xi Li², Yangang Wang³, Benhua Wang⁴, Xiangzhi Song⁵

Affiliations

¹ College of Chemistry & Chemical Engineering, Central South University, Changsha 410083, PR China.
² College of Biological Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, PR China.
³ College of Biological Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, PR China. Electronic address: ygwang8136@mail.zjxu.edu.cn.
⁴ College of Chemistry & Chemical Engineering, Central South University, Changsha 410083, PR China. Electronic address: benhuawang@csu.edu.cn.
⁵ College of Chemistry & Chemical Engineering, Central South University, Changsha 410083, PR China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha 410083, PR China. Electronic address: xzsong@csu.edu.cn.

PMID: 32795951
DOI: 10.1016/j.saa.2020.118755

Abstract

Due to the crucial biological roles of hydrogen polysulfides (H₂S_n) in living systems, the selective determination of H₂S_n is essential. In this work, we reported a turn-on fluorescent probe, JSI-Sn, for H₂S_n with high sensitivity and good selectivity. Probe JSI-Sn displayed a near-infrared emission (λ_max^Em = 701 nm) and a large Stokes shift (123 nm) in the presence of H₂S_n in solution. Using probe JSI-Sn as an indispensable tool, the monitoring of intracellular H₂S_n in living cells and zebrafish were realized.

Keywords: Bioimaging; Fluorescent probe; Hydrogen polysulfides; Large Stokes shift; Near-infrared.

MeSH terms

Animals
Fluorescent Dyes*
Hydrogen*
Sulfides
Zebrafish

Substances

Fluorescent Dyes
Sulfides
Hydrogen
polysulfide