[Application of medical biomaterials in prevention and treatment of tendon adhesion]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2020 Aug 15;34(8):1065-1070. doi: 10.7507/1002-1892.201910024.
[Article in Chinese]

Abstract

Objective: To review the research progress of medicine biomaterials in prevention and treatment of adhesion after tendon injury, and to provide reference for clinical treatment.

Methods: The literature on the application of medical biomaterials in the prevention and treatment of tendon adhesions in recent years was reviewed, and the biological process, treatment methods, and current status of tendon adhesions were summarized.

Results: Tendon adhesion as part of the healing process of the tendon is the biological response of the tendon to the injury and is also a common complication of joint dysfunction. Application of medical biomaterials can achieve better biological function of postoperative tendon by reducing the adhesion of peritendon tissues as far as possible without adversely affecting the tendon healing process.

Conclusion: The use of medical biomaterials is conducive to reduce the adhesion of tendon after operation, and the appropriate anti-adhesion material should be selected according to the patients' condition and surgical needs.

目的: 对用于肌腱损伤后粘连防治的医用生物材料研究进展进行综述,为临床治疗提供参考。.

方法: 查阅近年国内外有关医用生物材料在肌腱损伤后粘连防治中应用的文献,总结肌腱粘连的生物学过程、治疗方法及现状。.

结果: 肌腱粘连作为肌腱愈合过程的一部分,是肌腱对损伤的生物学反应,同时也是导致关节功能障碍的常见并发症。医用生物材料可以在尽量避免对肌腱愈合产生不利影响的前提下,通过减少腱周组织粘连,实现术后肌腱更好的生物学功能。.

结论: 医用生物材料有利于减少肌腱术后粘连,应根据患者情况及手术需要选择合适的防粘连材料。.

Keywords: Biomaterials; prevention; repair; tendon adhesion; tendon injury.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials*
  • Humans
  • Tendon Injuries*
  • Tendons
  • Tissue Adhesions* / prevention & control
  • Wound Healing

Substances

  • Biocompatible Materials

Grants and funding

上海王正国创伤医学发展基金(2017KJB-GK-001);南方医科大学南方医院院长基金重点项目(2017A001)