The Vitamin D in Pregnancy Study: a prospective prebirth cohort in southern Australia

BMJ Open. 2020 Aug 13;10(8):e036003. doi: 10.1136/bmjopen-2019-036003.

Abstract

Purpose: The Vitamin D in Pregnancy Study is a long-term ongoing cohort study. It was conceived to explore relationships between maternal vitamin D status in pregnancy and offspring growth and development, and has since diversified to include a wide range of physical and mental health exposures and outcomes.

Participants: Recruitment was from the University Hospital Geelong (Barwon Health) antenatal clinic, Geelong, Victoria, Australia, between 2002 and 2004. 475 women were initially recruited, which resulted in 400 eligible mother-child pairs at birth.

Findings to date: The cohort has been followed up twice in pregnancy, at birth, and 1 year, 6 years and 11 years post birth. The study has reported an association between vitamin D in pregnancy and musculoskeletal health and body composition in the children.

Future plans: Subject to funding, there will be a prospective young adult follow-up. This profile aims to foster both cross-national and international collaborations with both existing and future data collection.

Keywords: bone; developmental Origins; paediatric; vitamin D.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Cohort Studies
  • Female
  • Humans
  • Infant, Newborn
  • Pregnancy
  • Pregnancy Complications* / epidemiology
  • Prospective Studies
  • South Australia
  • Victoria / epidemiology
  • Vitamin D
  • Vitamin D Deficiency* / epidemiology
  • Young Adult

Substances

  • Vitamin D