[Research progress of non-alcoholic fatty liver disease in postmenopausal women]

Zhonghua Gan Zang Bing Za Zhi. 2020 Jul 20;28(7):629-632. doi: 10.3760/cma.j.cn501113-20200525-00270.
[Article in Chinese]

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease with a risk of developing non-alcoholic hepatitis, cirrhosis and liver cancer. Postmenopausal women have an increased risk of developing metabolic diseases including NAFLD under the influence of various factors such as aging, endocrine and metabolic changes. This article summarizes the latest research of NAFLD in postmenopausal women to elaborate and analyze the epidemiological characteristics, correlation between NAFLD and postmenopause, possible pathogenesis as well as feasible prevention and treatment methods.

非酒精性脂肪性肝病(NAFLD)是常见的慢性肝病,有进展为非酒精性肝炎、肝硬化和肝癌的风险。女性绝经后,在年龄增加、内分泌和代谢改变多重因素作用下,增加了包括NAFLD在内的代谢性疾病的发生风险。现对近年来关于女性绝经后NAFLD的研究展开综述,以阐述女性绝经后NAFLD的流行病学特征,NAFLD与女性绝经的相关性,并分析其可能的发病机制和可行的防治方法。.

Keywords: Estrogen; Insulin resistance; Non-alcoholic fatty liver disease; Postmenopause.

Publication types

  • Review

MeSH terms

  • Female
  • Hepatitis
  • Humans
  • Liver Cirrhosis
  • Liver Neoplasms
  • Non-alcoholic Fatty Liver Disease* / epidemiology
  • Postmenopause
  • Risk Factors