[Sinus balloon dilation for treatment of chronic sinusitis: a systematic review and Meta-analysis]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 May;34(5):406-410;416. doi: 10.13201/j.issn.2096-7993.2020.05.005.
[Article in Chinese]

Abstract
in English, Chinese

Objective:To systematically assess the efficacy of sinus balloon dilation（SBCD） for patients with chronic rhinosinusitis（CRS）. Method:To research the references whose the contents were related to the randomized controlled trials of sinus balloon dilation for treatment of chronic sinusitis from PubMed, Embase, Cochrane Library, WanFang, CNKI and other databases from January 2000 to June 2019. Assessed the quality and extracted the data of these included references and made Meta analysis by RevMan5.3 software. Result:A total of 11 references in English and Chinese were included. Result:Of Meta analysis showed that the difference had no statistical significance between the SNOT-20 score which were based on the statistics measured 3 months later and 6 months later [3 months later, SMD=-0.30, 95%CI（-1.01-0.41）, P=0.40, 6 months later, SMD=-0.53, 95%CI（-3.22-2.16）, P=0.70]and the score in the control group. Lund-Mackay CT score [SMD＝-0.69, 95%CI（-0.72--0.66, P<0.00001） ]and VAS symptom score [SMD＝-1.67, 95%CI（-1.91--1.44）, P<0.00001]following SBCD versus FESS in the treatment of CRS had statistical significance. Besides, SBCD had a lower incidence [OR=0.29, 95%CI（0.14-0.59）, P=0.0007]to develop postoperative complications compared with that in the control group. Conclusion:Balloon dilation of sinuses can significantly relieve the symptoms of patients with chronic sinusitis, this effect is equal or even better. Moreover, the incidence of developing the postoperative complications is lower, which SBCD of CRS is worthy of clinical popularization.

目的：系统评价鼻窦球囊扩张（SBCD）治疗慢性鼻窦炎（CRS）患者的疗效。 方法：计算机检索PubMed、Embase、Cochrane Library、万方、中国知网等数据库，检索SBCD治疗CRS的随机对照试验的文献，时间限定为2000-01-2019-06进行筛选，并对纳入的文献进行质量评价、数据提取，使用RevMan 5.3软件进行Meta分析。 结果：共纳入11篇文献。Meta分析结果显示：SBCD组SNOT-20评分[术后3个月SMD=-0.30，95%CI（-1.01～0.41），P=0.40，术后6个月SMD=-0.53，95%CI（-3.22～2.16），P=0.70]与对照组比较差异无统计学意义；Lund-Mackay鼻窦CT评分[SMD＝-0.69，95%CI（-0.72～-0.66），P<0.00001]，VAS症状评分[SMD＝-1.67，95%CI（-1.91～-1.44），P<0.00001]与对照组比较差异有统计学意义；SBCD组与对照组比较，患者并发症发生率低[OR=0.29，95%CI（0.14～0.59），P=0.0007]。 结论：SBCD可改善CRS患者的症状，达到与传统治疗相同的效果，且术后并发症发生率低，值得临床进一步推广。.

Keywords: Meta-analysis; sinus balloon dilation; sinusitis.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Chronic Disease
  • Dilatation
  • Endoscopy
  • Humans
  • Paranasal Sinuses*
  • Rhinitis*
  • Sinusitis*
  • Treatment Outcome

Grants and funding

国家自然科学基金(No：81670914，No：81870707)；山西省青年科技研究基金(No：201801D221410)