The Prognostic Significance of RB and PI3K Pathway Alterations in IDH-Mutant Grade II/III Astrocytomas

J Neuropathol Exp Neurol. 2020 Sep 1;79(9):1019-1023. doi: 10.1093/jnen/nlaa083.

Authors

Timothy E Richardson¹, Jamie M Walker^{2

3}

Affiliations

¹ Department of Pathology, State University of New York, Upstate Medical University, Syracuse, New York.
² Department of Pathology, University of Texas Health Science Center, San Antonio, Texas.
³ Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, Texas.

PMID: 32791525
DOI: 10.1093/jnen/nlaa083

No abstract available

Publication types

Letter

MeSH terms

Astrocytoma / genetics*
Astrocytoma / mortality
Astrocytoma / pathology*
DNA Copy Number Variations
Humans
Isocitrate Dehydrogenase / genetics
Phosphatidylinositol 3-Kinases / genetics*
Prognosis
Retinoblastoma Binding Proteins / genetics*
Signal Transduction / genetics
Ubiquitin-Protein Ligases / genetics*

Substances

RB1 protein, human
Retinoblastoma Binding Proteins
Isocitrate Dehydrogenase
Ubiquitin-Protein Ligases