Preparation of a new magnetic ion-imprinted polymer and optimization using Box-Behnken design for selective removal and determination of Cu(II) in food and wastewater samples

Abstract

A new magnetic Cu(II) IIP (Fe₃O₄@IIP-IDC) is synthesized by polymerization of Imidazole-4,5-dicarboxylic acid functionalized Allyl chloride, and significant improvement of its performance has been compared. SPE parameters were optimized using Box-Behnken design to achieve the twin objectives of quantitative determination and removal of Cu(II). FLPSO kinetic model and BS isotherm model fits well with the capacity of 175 mg g^-1. Analytical figures of merit includes a linearity range of 10-5,000 µg L^-1 (R² = 0.9986), preconcentration factor of 50 after eluting with 5 mL of 1 M HNO₃, LOD of 1.03 µg L^-1 and LOQ of 4.5 µg L^-1. Accuracy was assessed by analysis of SRM (Standard Reference Material) and recovery experiments after spiking in food samples (Tea, coffee, chocolate, spinach, infant milk substitute) and battery wastewater. Ease of use, reusability (15 cycles), rapid adsorption and high selectivity makes it a promising candidate for efficient and selective removal and trace determination.

Keywords: BS isotherm; Cu(II); FAAS; Fractal-like kinetics; IIP; SPE.