Abstract
The type III bacterial Fc receptor isolated form a group C streptococcus has been conjugated to alkaline phosphatase and used as a tracer in a variety of direct and indirect immunoassays. These immunoassays have utilized specific antibodies prepared in species whose immunoglobulins are poorly reactive with the type I Fc receptor, staphylococcal protein A. The value of the type III Fc receptor as a tracer for immunoassays utilizing antibodies produced in sheep and goats is documented.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Alkaline Phosphatase
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Animals
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Enzyme-Linked Immunosorbent Assay / methods
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Humans
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Immunoenzyme Techniques
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Immunoglobulin G
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Immunoglobulins / analysis*
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Plasminogen / analysis*
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Receptors, Fc / immunology*
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Sheep
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Staphylococcal Protein A / immunology*
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Streptococcus / immunology*
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Streptokinase / analysis
Substances
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Immunoglobulin G
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Immunoglobulins
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Receptors, Fc
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Staphylococcal Protein A
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Plasminogen
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Alkaline Phosphatase
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Streptokinase