Autologous Bone Marrow Mononuclear Cell Transplantation Therapy Improved Symptoms in Patients with Refractory Diabetic Sensorimotor Polyneuropathy via the Mechanisms of Paracrine and Immunomodulation: A Controlled Study

Cell Transplant. 2020 Jan-Dec:29:963689720949258. doi: 10.1177/0963689720949258.

Abstract

Chinese Clinical Trial Registry, ChiCTR-TRC-12002570.URL: http://www.chictr.org.cn/showproj.aspx?proj=6981.

Keywords: autologous transplantation; bone marrow mononuclear cells; clinical trial; diabetic peripheral neuropathy.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bone Marrow Transplantation* / adverse effects
  • Cytokines / metabolism
  • Diabetic Neuropathies / complications
  • Diabetic Neuropathies / immunology*
  • Diabetic Neuropathies / therapy*
  • Female
  • Humans
  • Immunomodulation*
  • Intercellular Signaling Peptides and Proteins / metabolism
  • Male
  • Middle Aged
  • Paracrine Communication*
  • Polyneuropathies / complications
  • Polyneuropathies / immunology*
  • Polyneuropathies / therapy*
  • Prognosis
  • Transplantation, Autologous
  • Treatment Outcome

Substances

  • Cytokines
  • Intercellular Signaling Peptides and Proteins

Associated data

  • ChiCTR/ChiCTR-TRC-12002570