This study, for the first time, estimates the climate impacts of adopting green roofs and cool roofs on the seasonal urban climate of 16 cities that comprise the Yangtze River Delta metropolitan. We use a suite of regional climate simulation to compare the local climate impacts of the implementation of different roof strategies in summer and winter. The results indicate that in summer, the 2 m surface temperature reduced significantly when these two roof strategies are adopted, with peak reductions of 0.74 and 1.19 K for green roofs and cool roofs, respectively. The cooling impact of cool roofs is more effective than that of green roofs under the scenarios assumed in this study. Besides, rooted in the different mechanisms influencing urban heat flux, significant indirect effects were also observed: adopting cool roofs leads to a decreased precipitation in summer and an apparent reduction in wintertime temperatures in the urban area. Although cool roofs can be an effective way to reduce high temperatures during the summer, green roofs have fewer adverse impacts on other climate conditions. These results underline the need for comprehensive climate change policies that incorporate place-based solutions and extend beyond the nearly exclusive focus on summertime cooling.