Tuberculin Skin Testing Induces Bilateral Tuberculous Uveitis in a Junior High School Student

Ocul Immunol Inflamm. 2022 Jan 2;30(1):160-162. doi: 10.1080/09273948.2020.1778731. Epub 2020 Aug 12.

Abstract

We report a rare case of bilateral tuberculous uveitis associated with tuberculin skin testing (TST) in an otherwise healthy junior high school student. A 12-year-old boy presented with severely decreased vision in both eyes and a history of an intradermal PPD (purified protein derivative) skin test 12 days earlier. The best-corrected visual acuity (BCVA) was 20/1000 in both eyes (OU). Ocular examination showed multifocal grayish-yellow choroidal tubercles. Laboratory examinations, including T-SPOT.TB, revealed no abnormal findings. He was diagnosed with tuberculous uveitis. Combined corticosteriod and anti-tuberculosis therapy (ATT) was given. The BCVA improved to 20/25, and the choroidal tubercles faded away. Our case suggests that TST may induce bilateral uveitis in rare cases.

Publication types

  • Case Reports

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Child
  • Humans
  • Male
  • Students
  • Tuberculin
  • Tuberculin Test
  • Tuberculosis, Ocular* / diagnosis
  • Tuberculosis, Ocular* / drug therapy
  • Uveitis* / diagnosis
  • Uveitis* / drug therapy

Substances

  • Antitubercular Agents
  • Tuberculin