An Unexpected Case of Lisinopril-Associated Severe Hyponatremia

Yiran Jiang; Wenjing Cai; Meghane E Masquelin; Kaitlin Gordon

doi:10.7759/cureus.9039

An Unexpected Case of Lisinopril-Associated Severe Hyponatremia

Cureus. 2020 Jul 7;12(7):e9039. doi: 10.7759/cureus.9039.

Authors

Yiran Jiang¹, Wenjing Cai², Meghane E Masquelin³, Kaitlin Gordon¹

Affiliations

¹ Internal Medicine, University of Louisville School of Medicine, Louisville, USA.
² Internal Medicine, University of Louisville, Louisville, USA.
³ Family Medicine, University of Louisville School of Medicine, Louisville, USA.

Abstract

Angiotensin-converting enzyme (ACE) inhibitors are a class of medications that have formed the backbone of hypertension management. Of these medications, lisinopril is one of the most commonly used. While known serious side effects of all ACE inhibitors include angioedema and hyperkalemia, ACE inhibitor-associated hyponatremia has been rarely reported. We present a patient with severe hyponatremia associated with lisinopril use and discuss the link between hyponatremia and ACE inhibitors.

Keywords: ace inhibitors; hyponatremia; lisinopril; siadh.

Publication types

Case Reports