Microemulsions as nano-reactors for the solubilization, separation, purification and encapsulation of bioactive compounds

Adv Colloid Interface Sci. 2020 Sep:283:102227. doi: 10.1016/j.cis.2020.102227. Epub 2020 Aug 1.

Abstract

Bioactive components possess various functionalities and are most interested for different food, nutraceutical and pharmaceutical formulations. The current review will discuss the preparation methods and fabrication techniques to design microemulsions (MEs) for the solubilization, separation, encapsulation and purification of various agro-food bioactive compounds. ME systems have shown suitable potential in enhancing oil recovery, protein extraction, and isolation of bioactive compounds. Moreover, the capability of ME based systems as drug and nutraceutical delivery cargos, and synthesis of various organic and inorganic nanoparticles, especially using biopolymers, will be investigated. ME liquid membranes are also developed as nano-extractor/nano-reactor vehicles, capable of simultaneous extraction, encapsulation or even synthesis of hydrophilic and lipophilic bioactive compounds for food, nutraceutical and drug applications.

Keywords: Bioactive compounds; Encapsulation; Microemulsions; Nano-reactor; Separation; Solubilization.

Publication types

  • Review

MeSH terms

  • Capsules
  • Chemical Fractionation / instrumentation*
  • Emulsions
  • Membranes, Artificial
  • Nanotechnology / instrumentation*
  • Solubility

Substances

  • Capsules
  • Emulsions
  • Membranes, Artificial