Chemical and biological activities of faveleira (Cnidoscolus quercifolius Pohl) seed oil for potential health applications

Food Chem. 2021 Feb 1:337:127771. doi: 10.1016/j.foodchem.2020.127771. Epub 2020 Aug 4.

Abstract

Faveleira (Cnidoscolus quercifolius) is an emerging Brazilian plant, with seeds rich in edible oil. This study investigates physicochemical properties, chemical composition, thermal and oxidative stability, in vitro and in vivo toxicity, antioxidant, antinociceptive and anti-inflammatory activities of faveleira seed oil. It was observed that the oil has low acidity, value of peroxide, chlorophyll, carotenoids, β-carotene and high concentrations of unsaturated fatty acids. In addition to presenting thermal and oxidative stability and high total phenolic content, with vanillin, eugenol and quercetin were predominating. The oil showed no toxicity in vitro and in vivo, and presented antioxidant, anti-inflammatory and antinociceptive activities. These findings provide relevant and appropriate conditions for processing of faveleira seed oil as functional food.

Keywords: Bioactive activity; Edible oil; Fatty acids; Functional food; Phenolic compounds; Pigments.

MeSH terms

  • Analgesics / chemistry
  • Analgesics / pharmacology
  • Analgesics / therapeutic use
  • Animals
  • Antioxidants / chemistry
  • Brazil
  • Carotenoids / analysis
  • Cell Survival / drug effects
  • Chlorophyll / analysis
  • Euphorbiaceae / chemistry
  • Euphorbiaceae / metabolism*
  • Fatty Acids / analysis
  • Male
  • Mice
  • Pain / chemically induced
  • Pain / prevention & control
  • Phenols / analysis
  • Plant Oils / chemistry*
  • Plant Oils / pharmacology
  • Plant Oils / therapeutic use
  • RAW 264.7 Cells
  • Seeds / chemistry
  • Seeds / metabolism

Substances

  • Analgesics
  • Antioxidants
  • Fatty Acids
  • Phenols
  • Plant Oils
  • Chlorophyll
  • Carotenoids