The HScore for secondary hemophagocytic lymphohistiocytosis, calculated without a marrow biopsy, is consistently low in patients with COVID-19

Int J Lab Hematol. 2020 Dec;42(6):e270-e273. doi: 10.1111/ijlh.13310. Epub 2020 Aug 10.

Authors

Giuseppe G Loscocco¹, Danilo Malandrino², Simone Barchiesi², Andrea Berni², Loredana Poggesi², Paola Guglielmelli¹, Alessandro M Vannucchi¹

Affiliations

¹ Department of Experimental and Clinical Medicine, CRIMM, Centro di Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy.
² Internal Medicine Unit 3, Department of Experimental and Clinical Medicine, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy.

PMID: 32776691
DOI: 10.1111/ijlh.13310

No abstract available

Publication types

Letter
Validation Study

MeSH terms

Aged
Aged, 80 and over
Betacoronavirus*
Blood Cell Count
Bone Marrow Examination
C-Reactive Protein / analysis
COVID-19
Comorbidity
Coronavirus Infections / blood
Coronavirus Infections / complications*
Female
Ferritins / blood
Humans
Interleukin-6 / blood
L-Lactate Dehydrogenase / blood
Lymphohistiocytosis, Hemophagocytic / diagnosis*
Lymphohistiocytosis, Hemophagocytic / etiology
Male
Middle Aged
Oxygen / blood
Pandemics
Partial Pressure
Pneumonia, Viral / blood
Pneumonia, Viral / complications*
Respiratory Distress Syndrome / blood
Respiratory Distress Syndrome / etiology
Respiratory Distress Syndrome / mortality
SARS-CoV-2
Sensitivity and Specificity

Substances

IL6 protein, human
Interleukin-6
C-Reactive Protein
Ferritins
L-Lactate Dehydrogenase
Oxygen