Calcium pyrophosphate deposition disease: The role of imaging in their detection and in differential diagnosis of crystal arthropathies

Antonio Catelli; Pietro Venetucci; Anna Castaldo; Giovanni Loiudice; Filippo Rosati Tarulli; Mariapaola Carpiniello; Mariateresa De Angelis; Antonio Corvino

doi:10.1016/j.radcr.2020.07.012

Calcium pyrophosphate deposition disease: The role of imaging in their detection and in differential diagnosis of crystal arthropathies

Radiol Case Rep. 2020 Aug 4;15(10):1773-1776. doi: 10.1016/j.radcr.2020.07.012. eCollection 2020 Oct.

Authors

Antonio Catelli¹, Pietro Venetucci¹, Anna Castaldo¹, Giovanni Loiudice¹, Filippo Rosati Tarulli², Mariapaola Carpiniello³, Mariateresa De Angelis³, Antonio Corvino⁴

Affiliations

¹ Advanced Biomedical Sciences Department, University Federico II of Naples (UNINA), via S. Pansini 5, I-80131 Naples, Italy.
² University of Salerno - Via Giovanni Paolo II, Fisciano (SA), Italy.
³ University of Campania "Luigi Vanvitelli", Caserta, Italy.
⁴ Motor Science and Wellness Department, University of Naples "Parthenope", Naples, Italy.

Abstract

Calcium pyrophosphate deposition disease is characterized by the deposition of pyrophosphate crystals in various joint structures. Calcium pyrophosphate deposition disease can be linked to underlying metabolic disorders such as hemochromatosis, hyperparathyroidism, hypophosphatemia, hypomagnesaemia, and hypothyroidism, all of which increase the risk of calcium pyrophosphate deposition. We present the case of a 55-year-old male who underwent diagnostic examination for the onset of recurrent joint pain in the right knee.

Keywords: CPPD; CT; Chondrocalcinosis; Imaging arthropathy; Pseudogout; US.

Publication types

Case Reports