Diagnosis and radio-guided surgery of lung nodules

Rev Esp Med Nucl Imagen Mol (Engl Ed). 2020 Sep-Oct;39(5):327-336. doi: 10.1016/j.remn.2020.06.014. Epub 2020 Aug 6.
[Article in English, Spanish]

Abstract

The detection of pulmonary nodules has increased in recent decades due to the introduction of lung cancer screening programs and the massively use of routine chest computed tomography in patients with malignant neoplasms. Percutaneous biopsy of these nodules does not always characterize them, so sometimes a surgical biopsy is necessary, which often requires a presurgical localization. The radioguided occult lesion localization (ROLL) described for breast lesions was first applied in the resection of pulmonary nodules in 2000, becoming an alternative to other presurgical localization techniques such as hook-wire. The technique provides high detection rate with minimal morbidity, enhancing multidisciplinary work with specialists in Radiology and Chest Surgery. The present paper describes the different pre-surgical localization techniques currently available, the methodological procedure of the ROLL technique and the collected results in 20 years of experience.

Keywords: Cirugía radioguiada; ROLL; Radioguided surgery; Solitary pulmonary nodule; nódulo pulmonar solitario.

MeSH terms

  • Early Detection of Cancer
  • Evidence-Based Medicine
  • Fiducial Markers
  • Humans
  • Intraoperative Period
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / surgery
  • Multiple Pulmonary Nodules / diagnostic imaging*
  • Multiple Pulmonary Nodules / surgery
  • Pneumonectomy
  • Positron Emission Tomography Computed Tomography / methods*
  • Positron-Emission Tomography
  • Punctures
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Solitary Pulmonary Nodule / diagnostic imaging*
  • Solitary Pulmonary Nodule / surgery
  • Staining and Labeling / methods
  • Surgery, Computer-Assisted / methods*
  • Thoracic Surgery, Video-Assisted
  • Tomography, X-Ray Computed
  • Ultrasonography

Substances

  • Radiopharmaceuticals