Respiratory and atopic conditions in children two to four years after the 2014 Hazelwood coalmine fire

Med J Aust. 2020 Sep;213(6):269-275. doi: 10.5694/mja2.50719. Epub 2020 Aug 8.

Abstract

Objective: To evaluate associations between exposure during early life to mine fire smoke and parent-reported indicators of respiratory and atopic illness 2-4 years later.

Design, setting: The Hazelwood coalmine fire exposed a regional Australian community to markedly increased air pollution during February - March 2014. During June 2016 - October 2018 we conducted a prospective cohort study of children from the Latrobe Valley.

Participants: Seventy-nine children exposed to smoke in utero, 81 exposed during early childhood (0-2 years of age), and 129 children conceived after the fire (ie, unexposed).

Exposure: Individualised mean daily and peak 24-hour fire-attributable fine particulate matter (PM2.5 ) exposure during the fire period, based on modelled air quality and time-activity data.

Main outcome measures: Parent-reported symptoms, medications use, and contacts with medical professionals, collected in monthly online diaries for 29 months, 2-4 years after the fire.

Results: In the in utero exposure analysis (2678 monthly diaries for 160 children exposed in utero or unexposed), each 10 μg/m3 increase in mean daily PM2.5 exposure was associated with increased reports of runny nose/cough (relative risk [RR], 1.09; 95% CI, 1.02-1.17), wheeze (RR, 1.56; 95% CI, 1.18-2.07), seeking health professional advice (RR, 1.17; 95% CI 1.06-1.29), and doctor diagnoses of upper respiratory tract infections, cold or flu (RR, 1.35; 95% CI, 1.14-1.60). Associations with peak 24-hour PM2.5 exposure were similar. In the early childhood exposure analysis (3290 diaries for 210 children exposed during early childhood, or unexposed), each 100 μg/m3 increase in peak 24-hour PM2.5 exposure was associated with increased use of asthma inhalers (RR, 1.26; 95% CI, 1.01-1.58).

Conclusions: Exposure to mine fire smoke in utero was associated with increased reports by parents of respiratory infections and wheeze in their children 2-4 years later.

Keywords: Air pollutants; Atopy; Child health; Emergencies; Population health; Respiratory tract infections.

MeSH terms

  • Air Pollution
  • Australia / epidemiology
  • Child, Preschool
  • Coal
  • Female
  • Fires*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Maternal Exposure / adverse effects*
  • Particulate Matter / analysis
  • Pregnancy
  • Prospective Studies
  • Regression Analysis
  • Respiratory Sounds / etiology*
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / etiology*
  • Smoke / adverse effects*
  • Smoke / analysis

Substances

  • Coal
  • Particulate Matter
  • Smoke