Cervical rhabdomyoma a rare entity: Case report with review of literature

Indian J Pathol Microbiol. 2020 Jul-Sep;63(3):467-469. doi: 10.4103/IJPM.IJPM_73_19.

Abstract

Genital rhabdomyomas are extremely rare benign tumors of skeletal muscle origin, majority of them being reported in vaginal location. Extensive literature search revealed only three such cases reported in cervix. We hereby report fourth such case of cervical rhabdomyoma in a 35-years-old female patient. The diagnosis was confirmed by histomorphology with desmin and myoD1 positivity on immunohistochemistry. Due to paucity of cases no definite treatment guidelines are available. Differentiation from identical and more common malignant counterpart which is rhabdomyosarcoma is essential to avoid unnecessary aggressive therapy.

Keywords: Cervical polyp; cervical rhabdomyoma; genital rhabdomyoma; myo D1; rhabdomyoblast.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Biomarkers, Tumor
  • Desmin / genetics
  • Diagnosis, Differential
  • Female
  • Humans
  • MyoD Protein / genetics
  • Precancerous Conditions / diagnosis
  • Rhabdomyoma / diagnosis*
  • Rhabdomyoma / genetics
  • Rhabdomyosarcoma / diagnosis
  • Uterine Cervical Neoplasms / diagnosis*

Substances

  • Biomarkers, Tumor
  • Desmin
  • MyoD Protein
  • MyoD1 myogenic differentiation protein