Intranasal steroid therapy - EPOS 2020

Otolaryngol Pol. 2020 Jun 30;74(3):41-49. doi: 10.5604/01.3001.0014.2449.

Abstract

Introduction: Due to their strong, multidirectional anti-inflammatory activity, intranasal glucocorticoids are the mainstay of treatment in rhinosinusitis, including acute rhinosinusitis, chronic rhinosinusitis, and chronic rhinosinusitis with nasal polyps, as well as allergic rhinitis. Owing to its high systemic safety and high anti-inflammatory efficacy, mometasone furoate - a new-generation intranasal glucocorticoid - was approved in 2019 as an over-the-counter medication for Polish patients diagnosed with allergic rhinitis. Scientific societies and expert groups recommend the use of intranasal glucocorticoids in a much broader range of indications. In February 2020, an updated version of the European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS 2020) was published.

Aim: This article discusses the role of nasal glucocorticoids in regimens used in the treatment of nasal sinusitis as published in EPOS 2020 with Polish country-specific realities being taken into account.

Keywords: EPOS 2020; glucocorticoids; rhinosinusitis.

MeSH terms

  • Administration, Intranasal
  • Anti-Inflammatory Agents / therapeutic use*
  • Glucocorticoids / therapeutic use*
  • Humans
  • Nasal Sprays
  • Poland
  • Practice Guidelines as Topic
  • Rhinitis / drug therapy*
  • Rhinitis / prevention & control
  • Sinusitis / drug therapy*
  • Sinusitis / prevention & control

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Nasal Sprays