Abstract
A family of five heteroleptic complexes [Ru(C^N)(N^N)2][PF6] (HC^N = methyl 1-butyl-2-arylbenzimidazolecarboxylate; N^N = polypyridine) has been synthesized to act as biologically-compatible green light photosensitizers (PSs) with phototherapeutic indexes (PIs) up to higher than 700 under hypoxia (2% O2) in HeLa cancer cells under short time of irradiation.
MeSH terms
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Benzimidazoles / chemistry
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Coordination Complexes / chemistry*
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Coordination Complexes / pharmacology*
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HeLa Cells
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Humans
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Light*
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Photosensitizing Agents / chemistry
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Photosensitizing Agents / pharmacology
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Ruthenium / chemistry*
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Tumor Hypoxia / drug effects*
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Tumor Hypoxia / radiation effects*
Substances
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Benzimidazoles
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Coordination Complexes
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Photosensitizing Agents
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Ruthenium
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benzimidazole