Influence of Acromial Morphologic Characteristics and Acromioclavicular Arthrosis on the Effect of Platelet-Rich Plasma on Partial Tears of the Supraspinatus Tendon

AJR Am J Roentgenol. 2020 Oct;215(4):954-962. doi: 10.2214/AJR.19.22331. Epub 2020 Jul 8.

Abstract

OBJECTIVE. The purposes of this study were to determine the medium-term effect of ultrasound-guided infiltration of platelet-rich plasma (PRP) on partial tears of the supraspinatus tendon (SST) and to identify prognostic indicators of an unfavorable outcome. SUBJECTS AND METHODS. Over a period of 4 years, patients with a partial SST tear smaller than 1.5 cm referred for ultrasound-guided PRP infiltration (1 mL) for shoulder pain lasting more than 3 months were recruited consecutively. MRI was used to analyze the type of acromion and presence of acromioclavicular (AC) arthrosis. Primary (size of the tear and associated bursitis) and secondary (mobility and pain) results were collected at 3 months. RESULTS. The study included 128 patients (66 men, 62 women; mean age, 48.3 years; range, 20-59 years). At 3 months, favorable evolution of the tear repair was recorded in 71.1% (91/128) of patients and resolution of bursitis in 66.7% (42/63). Changes in tear size had large effect sizes (Cohen d ≥ 1.16), as did pain and shoulder mobility (Cohen d ≥ 0.95). The strongest predictors of unfavorable evolution of tear and bursitis were type 3 acromion and types 1 and 2 acromion with AC arthrosis (p < 0.001; β = 20.412). CONCLUSION. Ultrasound-guided PRP infiltration of partial tears of the SST relieves pain and improves shoulder mobility, but its effect on the size of the tear is influenced by the morphologic characteristics of the acromion and the presence of AC arthrosis. The effect of PRP is insufficient in patients with a type 3 acromion or severe AC arthrosis.

Keywords: acromion; morphology; platelet-rich plasma; supraspinatus; tendon tear; ultrasound-guided infiltration.

MeSH terms

  • Acromioclavicular Joint*
  • Acromion / diagnostic imaging
  • Acromion / pathology*
  • Adult
  • Bursitis / diagnostic imaging
  • Bursitis / etiology
  • Bursitis / therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Osteoarthritis / complications*
  • Platelet-Rich Plasma*
  • Prospective Studies
  • Range of Motion, Articular
  • Rotator Cuff Injuries / complications
  • Rotator Cuff Injuries / diagnostic imaging
  • Rotator Cuff Injuries / therapy*
  • Shoulder Joint
  • Shoulder Pain / diagnostic imaging
  • Shoulder Pain / etiology
  • Shoulder Pain / therapy
  • Treatment Outcome
  • Ultrasonography, Interventional*
  • Young Adult