Chronic, Recurrent Bacterial Endophthalmitis Caused by Achromobacter xylosoxidans: Clinical Features and Management

Thomas A Lazzarini; Hasenin Al-Khersan; Nimesh A Patel; Nicolas A Yannuzzi; Jaime D Martinez; Diego Altamirano; Lizt K Torres; Darlene Miller; Juan F Batlle; Guillermo Amescua; Harry W Flynn Jr

doi:10.2147/IMCRJ.S259899

Chronic, Recurrent Bacterial Endophthalmitis Caused by Achromobacter xylosoxidans: Clinical Features and Management

Int Med Case Rep J. 2020 Jul 9:13:265-269. doi: 10.2147/IMCRJ.S259899. eCollection 2020.

Affiliations

¹ Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
² Laser Center, Santo Domingo, Dominican Republic.

Abstract

A 79-year-old man presented to a tertiary referral center from the Dominican Republic with an opaque corneal graft and a diagnosis of chronic, recurrent culture-positive Achromobacter xylosoxidans endophthalmitis of the left eye. The patient had a history of penetrating keratoplasty for Fuchs' dystrophy and had undergone multiple intraocular surgeries including pars plana vitrectomy and anterior chamber wash out for the diagnosis and management of chronic endophthalmitis. After being referred, the patient underwent a third PKP, removal of his intraocular lens (IOL), capsulectomy, and injection of intravitreal antibiotics. All surgical specimens demonstrated the growth of A. xylosoxidans. Five months after surgery, the graft remained clear without evidence of infection and best-corrected visual acuity was 20/350.

Keywords: Achromobacter xylosoxidans; endophthalmitis; ophthalmic infection; ophthalmlology; postoperative endophthalmitis.

Publication types

Case Reports

Grants and funding

Funding was generously provided by NIH-funded 2P30 Vision Core Center Grant (EY14801-16) and a Research to Prevent Blindness Unrestricted Grant (GR004596).