New Compounds from the Roots of Corsican Calicotome Villosa (Poir.) Link.: Two Pterocarpans and a Dihydrobenzofuran

Molecules. 2020 Jul 30;25(15):3467. doi: 10.3390/molecules25153467.

Abstract

Three new compounds, a dihydrobenzofuran (coumaran) derivative (compound 1) and two pterocarpans (compounds 2 and 3) were isolated from a root extract of Calicotome villosa growing wild in Corsica. Their structures were elucidated using 1D and 2D NMR spectroscopy and MS/MS as 2-(1-methylethenyl)-5-hydroxy-6-carbomethoxy-2,3-dihydro-benzofuran, 4,9-dihydroxy-3-methoxy-2-dimethylallylpterocarpan, and 4,9-dihydroxy-3',3'-dimethyl-2,3-pyranopterocarpan.

Keywords: 1D and 2D NMR; Calicotome villosa; dihydrobenzofuran; pterocarpan; root extract.

MeSH terms

  • Benzofurans / analysis
  • Benzofurans / chemistry*
  • Benzofurans / isolation & purification
  • Fabaceae / chemistry*
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Extracts / analysis
  • Plant Extracts / chemistry*
  • Plant Extracts / isolation & purification
  • Plant Roots / chemistry
  • Pterocarpans / analysis
  • Pterocarpans / chemistry*
  • Pterocarpans / isolation & purification

Substances

  • Benzofurans
  • Plant Extracts
  • Pterocarpans