The Emergence of Autism Symptoms Prior to 18 Months of Age: A Systematic Literature Review

J Autism Dev Disord. 2021 Mar;51(3):973-993. doi: 10.1007/s10803-020-04618-w.

Abstract

Pre-diagnostic intervention for autism spectrum disorder (ASD) allows symptoms to be addressed as they emerge, often between six to 18 months, rather than after the full onset of the disorder. A systematic literature review, spanning the previous six years was conducted in order to provide an updated review looking at the earliest behavior symptoms of ASD. All included studies used a prospective experimental design, reported on symptoms that emerged before 18-months of age, exclusively in children who would later receive a diagnosis, and were assessed for quality. This review is the first to address this research question through the use of a systematic research design and extends the literature by following up on recommendations for future research from previous findings.

Keywords: Autism spectrum disorders; Early behavioral symptoms; Early screening; Systematic literature review.

Publication types

  • Systematic Review

MeSH terms

  • Autism Spectrum Disorder / diagnosis*
  • Autism Spectrum Disorder / psychology*
  • Child Development / physiology*
  • Early Diagnosis
  • Female
  • Humans
  • Infant
  • Language Development
  • Male
  • Motor Skills / physiology
  • Prospective Studies