Abstract
Conjugate Sn(iv)(pyropheophorbide a)dichloride-(peptide nucleic acid) catalyzes reduction of azobenzene derivatives in the presence of complementary nucleic acid (NA) upon irridiation with red light (660 nm). This is the first red light-induced NA-templated photoreduction. It is highly sensitive to single mismatches in the NA-template and can detect down to 5 nM NAs.
MeSH terms
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Azo Compounds / chemistry
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Base Sequence
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Catalysis
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Chlorophyll / analogs & derivatives
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Chlorophyll / chemistry
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Coordination Complexes / chemistry
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Light*
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Limit of Detection
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Nucleic Acids / analysis*
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Nucleic Acids / chemistry
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Oxidation-Reduction
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Peptide Nucleic Acids / chemistry
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Tin / chemistry
Substances
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Azo Compounds
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Coordination Complexes
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Nucleic Acids
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Peptide Nucleic Acids
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Chlorophyll
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pyropheophorbide a
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Tin
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azobenzene