[Progress in the surgical treatment of trigeminal schwannoma]

Zhonghua Wai Ke Za Zhi. 2020 Aug 1;58(8):653-656. doi: 10.3760/cma.j.cn112139-20200118-00041.
[Article in Chinese]

Abstract

Trigeminal schwannomas(TSs) is the second most common intracranial schwannomas next to acoustic neuroma. These uncommon, slow-growing tumors, which prove to originated from Schwann cells of the fifth brain nerve, can achieve their development into various compartments.Previous to the era of microsurgery, the total tumor resection rate was low, and the postoperative neurological function was seriously damaged.With the development of microsurgery and skull base approach, the microsurgery effect of TSs has been improved. Besides, neuroendoscopy is also used in the operation of some types of trigeminal schwannomas. Radiation therapy can be performed to control tumor growth for the patients who cannot tolerate surgery, have small tumor volume, have residual tumor tissue or relapse.

三叉神经鞘瘤(TSs)是第二大常见的颅内神经鞘瘤,仅次于听神经瘤。TSs起源于第五脑神经的施万细胞,可于一个或多个间隙中生长,生长模式复杂。显微神经外科技术的成熟和颅底手术入路的不断发展改变了TSs全切除率低且术后神经功能受损严重的历史,使TSs患者的预后不断改善。目前,神经内镜也应用于部分类型TSs的外科治疗中,并获得良好效果。对于不能耐受手术、肿瘤体积小、手术残留肿瘤组织或复发的患者可进行放疗以控制肿瘤生长。.

Keywords: Microsurgery; Neurilemmoma; Neuroendoscopy; Trigeminal nerve.

MeSH terms

  • Cranial Nerve Neoplasms / radiotherapy
  • Cranial Nerve Neoplasms / surgery*
  • Humans
  • Microsurgery
  • Neurilemmoma / radiotherapy
  • Neurilemmoma / surgery*
  • Neuroendoscopy
  • Treatment Outcome
  • Trigeminal Nerve Diseases / radiotherapy
  • Trigeminal Nerve Diseases / surgery*